活動状況

[シンポジウム] 6月21日〜22日に第2回国際シンポジウムを開催します。

2023.06.14

The 2nd International Symposium on REPLICATION of NON GENOME

共催:東京大学医科学研究所 国際共同利用・共同研究拠点


Cutting Edge of Epigenetics


Date & Time:June 21 (Wed) 10:00-18:00 – June 22 (Thu) 9:30-15:00, 2023
Venue: Tsuki-no-Sumika, Atami Juraku Hotel, Shizuoka, Japan
Language:  English
Organizer: Makoto Nakanishi

June 21 (Wed) 10:00 – 18:00


10:00 – 10:05
Makoto Nakanishi (The Univ. of Tokyo, Japan)
Opening remarks


Session 1 Epigenetics in Gametogenesis & Development


10:05 – 10:35
Masato Ikawa (Osaka University, Japan)
Testis-enriched genes and their functions for spermatogenesis and fertilization

10:35 – 11:00
Akihiko Sakashita (Keio University, Japan)
The role of retrotransposon MERVL in regulating host gene expression and ontogeny

11:00 – 11:15: Coffee Break


Session 2 Epigenetics in Chromatin Regulation PartI

11:15 – 11:45
Takashi Fukaya (The Univ. of Tokyo, Japan)
Visualization of transcription hubs in living Drosophila embryos

11:45 – 12:20
Huck Hui Ng (Genome Institute of Singapore, Singapore)
Dissecting the genetic and epigenetic pathways for non-alcoholic fatty liver diseases

12:20 – 13:35
Lunch

Session 3 Epigenetics in Chromatin Regulation PartII

13:35 – 14:10
Anja Groth (University of Copenhagen, Denmark)
Chromatin Replication and Epigenome Maintenance 

14:10 – 14:40
Katsuhiko Shirahige  (The Univ. of Tokyo, Japan)
Is Cohesin Really Necessary for Transcription? Molecular Entities of Transcriptional Dysregulation in the absence of Cohesin

14:40 – 15:00 Coffee Break

15:00 – 15:30
Yoichi Shinkai (RIKEN, Japan)
Epigenetic plasticity safeguards heterochromatin configuration

15:30 – 16:05
William J. Greenleaf (Stanford University, USA
Exploring the physical genome

16:05 – 16:10
Comments from the Advisory Bord
Group Photo

16:10 – 18:00
Poster session

19:00 –
Dinner & Reception


June 22 (Thu) 9:30 – 15:00


Session 4 Epigenetics in Transcriptional Regulation

9:30 – 9:55
Haruhiko Koseki (RIKEN, Japan)
Polycomb in DNA damage response

9:55 – 10:30

Kristian Helin (The institute of Cancer Research, UK)
Interrogating the functional roles of histone methylation in transcription

10:30 – 11:00 Coffee Break


Session 5 Epigenetics in DNA Methylation


11:00 – 11:25
Atsushi Iwama (The Univ. of Tokyo, Japan)
TOPORS ubiquitin ligase promotes DNMT1 degradation upon DNA hypomethylating agents

11:25 – 11: 50

Kyohei Arita (Yokohama City University, Japan)
Structural basis for activation mechanism of DNMT1

11:50 – 12: 15
Makoto Nakanishi (The Univ. of Tokyo, Japan)
Molecular mechanism of replication-uncoupled maintenance DNA methylation

12:15 – 13:45
Lunch

Session 6 Epigenetics in Germ Line Stem Cell Biology


13:45 – 14:10
Kei-ichiro Ishiguro (Kumamoto University, Japan)
Mechanism of cell cycle switch from mitosis to meiosis in mouse germ cells

14:10 – 14:45
Xin Chen (Johns Hopkins University, USA)
Breaking Symmetry: Asymmetric Histone Inheritance

14:45 – 14:55
Comments from the Advisory Board

14:55 – 15:00

Hiroyuki Aburatani (The University of Tokyo, Japan) Closing remarks



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